Tag: immuno-oncology 2 results

Oncology & Hematology

Proactive AE Management in Oncology Trials: Moving Medical Strategy Upstream 

Advances in oncology are expanding what is therapeutically possible while also introducing new complexity into clinical trial execution. Immune-based therapies, cellular therapies, bispecifics, and other emerging modalities can produce toxicity profiles that differ substantially from those associated with traditional cytotoxic...

Cell & Gene Therapy

A Primer on Cancer Immunotherapy Part 1: Goals & Major Approaches

In recent years, immunotherapy has led to substantial advances in cancer therapy. In particular, the immune checkpoint inhibitors — PD-1/PD-L1 and CTLA-4 inhibitors — have revolutionized treatment for certain hematologic malignancies and solid tumors. The U.S. Food and Drug Administration...