Premier Insight 259: In Clinical Trials, Success Isn’t Always Where You Expect It

When does a clinical trial that falls short of its goal still constitute success? When the experience reveals invaluable lessons in how to avoid a repeat performance — and identifies a highly productive location for siting future studies. A large, multinational study of a drug to control inflammation in patients with recurring high-grade malignant glioma was in trouble. It had been underway for a year, and its data collection was compromised from the start when a requirement that all MRIs be read at a single facility proved unworkable.